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When comedian and TV host Sandi Toksvig came out as gay in the early 1990s, she used humor to recover from the onslaught of vitriol.Today, she says, humor can help bring about social change.

While Uber wades through crisis after crisis, media mogul Arianna Huffington, the sole woman on its board, is emerging as chief of culture change.

The U.S. considers deploying hundreds more American troops to Syria in the final phase of the war against ISIS — one that could reshape borders and relationships in the Middle East.

Researchers have long known behavior, environment and genetics play a role in cancer. A study in Science finds luck is also a major factor. Nearly two-thirds of cancer mutations arise randomly.

Middle-aged white people without college degrees are increasingly likely to die of suicide, or drug and alcohol abuse. The lack of a pathway to solid jobs is one reason why, two economists say.

A surge of refugees is leaving America for Canada as they look for a more secure future. Refugees are quickly vetted by border agents and given access to shelter, health care and a work permit.

Research hasn't yet confirmed the early hints that a mix of IV vitamins and steroids might stop the fatal organ failure of sepsis. But an effective treatment for sepsis would be a really big deal.

President Trump's properties have been attracting a large and generous circle of buyers, from wealthy Russians to a Chinese businesswoman. Many questions are being raised about the deals' ethics.

Secretary of State Rex Tillerson is hosting officials from 68 countries to discuss how best to take on ISIS. "As a coalition we are not in the business of nation-building or reconstruction," he said.

Caps in the GOP health plan have huge implications for people over 65. In addition to helping low-income seniors with long-term care, Medicaid helps pay for some of their Medicare premiums and copays.

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